Fig. 2
From: 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice
Hippocampal slices treated with 4R after NMDA insult showed recovery in both WT and α7KO mice. a Experimental timeline. b Representative final population spike recordings. c Population spike % recovery of 4R pre- and post-NMDA treatment in WT and α7KO mice. d % recovery in ⍺7KO mice with and without DHβE (1 μM). e % recovery in WT mice in the presence of DHβE (1 μM) or MLA (10 nM). Ordinary two-way ANOVA (c), ordinary one-way ANOVA (d), followed by Tukey’s post hoc test or nonparametric ANOVA test, followed by Dunn’s post hoc test (e). **p < 0.01, ***p < 0.001, **** p < 0.0001, versus NMDA; #p < 0.05, versus NMDA+4R+DHβE. Data are presented as mean ± SEM. n = 14–21 slices/treatment from 2–3 independent experiments