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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model

Fig. 5

Hypervascularization, microglia, astrocyte activation, and B cell accumulation in GF-IL23 cerebellum. Histology findings at d60. a–f GF-IL23 mice display hypervascularization (a), microglia, and astrocyte activation (c, e) compared to WT mice (b, d, f). g, h Fluorescent immunohistochemistry of GF-IL23 cerebellum reveals that the infiltrates consist of large amounts of B cells. Scale bar: 100 μm. The images are representative of those from at least 8 different transgenic/6 WT mice

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Journal of Neuroinflammation

ISSN: 1742-2094