Table 2 Proteins with strongest predictive value for infarct volume or edema volume based on location of blood sample. For directionality, if the relationship is positive, higher expression levels of that protein is associated with higher infarct/edema volume. If the relationship is negative, higher levels of that protein are associated with lower infarct/edema volume. Included in the table are R2 values for each predictive model
From: Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity
Protein | p value | Directionality |
|---|---|---|
Systemic blood and infarct volume R2=0.7551 | ||
APOM | <0.0001 | (−) |
MMP10 | 0.0006 | (+) |
DPP4 | <0.0001 | (−) |
CST3 | <0.0001 | (−) |
IL10RB | <0.0001 | (+) |
AOC3 | 0.0191 | (+) |
CXCL9 | <0.0001 | (+) |
VASN | 0.0009 | (+) |
IL20RA | 0.0038 | (+) |
IL18 | 0.0182 | (+) |
Intracranial blood and infarct volume R2=0.6665 | ||
SLAMF1 | <0.0001 | (+) |
CCL18 | <0.0001 | (+) |
NCAM1 | <0.0001 | (+) |
LILRB2 | 0.0359 | (−) |
CD59 | <0.0001 | (+) |
IGFBP6 | <0.0001 | (−) |
ANG | <0.0001 | (−) |
MEGF9 | 0.0087 | (−) |
MCP1 | 0.0001 | (−) |
ITGAM | 0.0053 | (−) |
Systemic blood and edema volume R2=0.6396 | ||
APOM | 0.0014 | (−) |
MMP10 | 0.0014 | (+) |
NT3 | <0.0001 | (−) |
PDL1 | <0.0001 | (−) |
SLAMF1 | <0.0001 | (+) |
CCL5 | <0.0001 | (+) |
ANG | <0.0001 | (−) |
CHL1 | <0.0001 | (−) |
ITGAM | <0.0001 | (−) |
CCL25 | <0.0001 | (+) |
Intracranial blood and edema volume R2=0.6564 | ||
CCL18 | <0.0001 | (+) |
SLAMF1 | <0.0001 | (+) |
FAP | <0.0001 | (−) |
PDL1 | <0.0001 | (−) |
TSLP | 0.1851 | (+) |
F7 | <0.0001 | (−) |
MBL2 | 0.0001 | (−) |
CSF1 | 0.0045 | (−) |
CCL11 | 0.0012 | (−) |
IL15RA | 0.0261 | (+) |