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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates

Fig. 8

Direct contact between microglia and astrocytes enables cell-to-cell transfer of αSYN deposits. Astrocytes and microglia were found to have direct TNTs (a, b). Z-stacks of the zoomed regions of a and b are shown beside respective image. High resolution imaging revealed TNT-mediated transfer of αSYN between astrocytes and microglia (c, d, white arrows). The microglia were also found to be in close contact with (e) or completely surrounded by astrocytic membranes (f). Scale bars= 20μm

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Journal of Neuroinflammation

ISSN: 1742-2094