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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain

Fig. 1

Schematic representation of the experimental design and procedures. a Establishment of a neuroinflammation model upon LPS injection in the rat striatum. The striatum was collected 7 days post-injection and further analysed for neuroinflammatory markers and N-glycomic profile. b Experimental plan of N-glycan characterisation. Regions of interest were either sectioned for MALDI-TOF-MSI or punched for N-glycan isolation and characterisation using HILIC-UPLC. The combination of both techniques allowed for the spatial and quantitative N-glycome profiling in the rat striatum

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