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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain

Fig. 5

Changes in the percentage fraction of fucosylated and sialylated N-glycans between LPS-injected striatum and contralateral (non-injected (NI)) striatum at seven days post-injection. a Proportion of total N-glycans decorated with either core or outer arm fucose (or both), considering the main glycan structure in each GP. b Percentage fraction of fucosylated N-glycans according to the degree of fucosylation (n = 1, 2, 3, 4), which includes both sialylated and unsialylated fucosylated glycans. Data presented as the mean ± SD, n = 5. Paired Student’s t test was used, and statistically significant difference was set at ****p < 0.0001. c Percentage fraction of sialylated N-glycans according to the degree of sialylation, considering the main glycan structure in each GP. d Percentage fraction of sialylated N-glycans according to the linkage of the sialic acid to galactose residue indicates the significantly high abundance of α(2-3)-linkage to galactose compared to that of α(2-6)-linkage. Data presented as the mean ± SD, n = 5. Paired Student’s t test was used, and statistical significant difference was set at ****p < 0.0001

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