Fig. 2From: Age influences susceptibility of brain capillary endothelial cells to La Crosse virus infection and cell deathHigher infection rate of weanling BCECs compared to adult BCECs in vitro. Weanling and adult BCECs were isolated from uninfected mice and then cultured in vitro until cells reached confluency. Cultures were infected with LACV at (a)Â 0.1, (b)Â 1, and (c)10 MOI for 1 h, washed, and then incubated for indicated time points. Data are plotted as the mean obtained from 3 or more different experimental samples and all individual plaque counts are shown. A two-way ANOVA was performed for statistical analysis. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001Back to article page