Fig. 1
Prior LPS compromised survival time and heat tolerance under heat exposure. The experiment was designed into four groups: control/no heat, control/heat, LPS/no heat, and LPS/heat groups. LPS treatment condition was 1 mg/kg and whole-body heating (WBH) temperature was 41.2 °C. a Survival curve was monitored in comparison between control/heat and LPS/heat groups. The statistical analysis was conducted by Log-rank test (n = 20), **p < 0.01, *p < 0.05. b Core temperature (TC) profiles of mice were monitored in every 15 min to compare among control/heat and LPS/heat groups. c Prior LTA compromised survival time under heat exposure. The animals were designed into four groups: control/no heat, control/heat, LTA/no heat, and LTA/heat groups. LTA treatment condition was 1 mg/kg and whole-body heating (WBH) temperature was 41.2 °C. Survival curve was monitored in comparison between control/heat and LTA/heat groups. The average time taken by core temperature to reach 42 °C was calculated as the mean ± SEM. (n = 5 to 10). **p < 0.01, *p < 0.05