Table 6 Metabolic parameters of THY-Tau22 and wt mice. Seven-month-old

Fasting glucose [mmol/l] (n = 7–8)

Male

8.98±0.43^#

10.80±0.80*

9.39±1.03^#

10.73±0.72

Cholesterol [mmol/l] (n = 7–8)

Male

1.06±0.16

1.64±0.26

0.88±0.05

1.87±0.13***

FFA [ng/ml] (n = 7–8)

Male

0.39±0.05

0.48±0.07

0.45±0.09

0.77±0.07*^{, +}

TG [mmol/l] (n = 7–8)

Male

0.48±0.11^#

0.63±0.12

0.36±0.03

0.78±0.08***

Leptin [ng/ml] (n = 7–8)

Male

3.22±0.49

70.76±19.41**

1.68±0.60

61.82±12.30***

Fasting glucose [mmol/l] (n = 7–8)

Female

7.47±0.84

9.61±0.38*

8.10±0.97^###

10.19±0.66

Cholesterol [mmol/l] (n = 7–8)

Female

0.57±0.03^##

1.23±0.08***

0.62±0.05^###

1.33±0.13***

FFA [ng/ml] (n = 7–8)

Female

0.40±0.08^#

0.46±0.03

0.52±0.08

0.56±0.04

TG [mmol/l] (n = 7–8)

Female

0.31±0.03

0.46±0.03**

0.58±0.28

0.40±0.02

Leptin [ng/ml] (n = 7–8)

Female

3.19±0.80^#

92.22±14.35***

2.95±0.27

42.06±12.20***^{, +}