Fig. 1From: Acute pre-operative ibuprofen improves cognition in a rat model for postoperative cognitive dysfunctionTime line of the experimental protocol. Ibuprofen (IBU)-treated rats (young n = 12; aged n = 11) received a single i.p. injection of ibuprofen 30 min before surgery; control (C) rats (young n = 14; aged n = 11) were handled. Rats were sacrificed (+) at day 14. Blood samples were collected at 30 min, and 1, 6, and 24 h after surgery and at sacrifice. Fecal samples were collected before and 7 days after surgery. MWM, Morris water mazeBack to article page