Fig. 5

A–J Changes of HMGB1, HSP70, and NF-κB p65 levels affected by cel under the OGD model were observed at 48 h by WB and IF in vitro. H–N Changes in HMGB1, HSP70, and NF-κB p65 levels were observed in the rat cerebral cortex by WB and rat cerebral cortex slices by IF. Error bars represent SEM. ^###p < 0.001 vs. control group (in vitro) or sham group (in vivo), *p < 0.05, **p < 0.01, ***p < 0.001 vs. model group based on a one-way analysis of variance was used (n = 4). Scale bar = 25 μm