Fig. 7From: Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brainCell type-specific expression of different ISGs. Successive FFPE sections of ADAR1K999N mice following in situ hybridization for ISG15 (A) or CXCL10 (B) and counterstaining with hematoxylin. A A discrete focus on neurons hybridizing for ISG15 (A) overlaps with a similarly constrained focus of CXCL10 hybridized microglia in the successive section (B). Bar = 100 μmBack to article page