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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Repeated neonatal sevoflurane induced neurocognitive impairment through NF-κB-mediated pyroptosis

Fig. 2

BAY 11-7082 suppresses sevoflurane-induced activation of canonical and non-canonical inflammatory caspases. A Representative real-time PCR analysis of the mRNA levels of NLRP3, caspase-1, and caspase-11 in the hippocampus in developing rats. B Representative western blotting and quantitative analysis of the protein levels of NLRP3, pro-caspase-1, and cleaved caspase-1 in the hippocampus in developing rats. C Representative western blotting and quantitative analysis of the protein levels of pro-caspase-11 and cleaved caspase-11 in the hippocampus in developing rats. Values are presented as mean ± SEM (n = 6 rats/group). *p < 0.05 versus the Con group; #p < 0.05 versus the Sev group

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