Fig. 6
From: Repeated neonatal sevoflurane induced neurocognitive impairment through NF-κB-mediated pyroptosis
BAY 11-7082 ameliorates sevoflurane-induced cognitive deficits in adolescent rats. A Total distance traveled and B time spent in the center in open field tests. The open field tests in developing rats were performed at PND 40. C Escape latency during the spatial training of MWM for five consecutive days. The MWM tests were performed at PND 50. D Time spent in the target quadrant and E crossing platform times in the probe trial of MWM. F Freezing time to context and G freezing time to tone in the fear conditioning tests. The fear conditioning tests were performed at PND 60. Values are presented as mean ± SEM (n = 12 rats/group). *p < 0.05 versus the Con group; #p < 0.05 versus the Sev group