Fig. 5

White matter immunohistochemistry. Glial fibrillary acidic protein (GFAP+), ionised calcium binding adaptor molecule (Iba-1+), amoeboid (Iba-1+) microglia, IL-1β immunoreactivity score, caspase 3, oligodendrocyte transcriptase factor-2 (Olig-2+) and 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase+) cell counts, % area fraction of CNPase staining, anti-adenomatous polyposis coli clone (CC1+) cell counts and % area fraction of myelin basic protein (MBP) in the periventricular white matter (PVWM), first and second intragyral white matter tracts (IGWM 1 and IGWM 2) in control (blue circles, n = 9), LPS+vehicle (red circles, n = 8) and LPS+IL-1Ra (green circles, n = 9) groups. Data are means ± SE. *P < 0.05 vs. control, #P = 0.06 vs. control