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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Asthmatic allergen inhalation sensitises carotid bodies to lysophosphatidic acid

Fig. 4

LPAr1 expression in carotid bodies of asthmatic and naïve rats. Lysophosphatidic acid receptor subtype 1 (LPAr1) is predominantly expressed in tyrosine hydroxylase (TH) positive cells which represent glomus cells of the carotid bodies (round cells with large nuclei as imaged with DAPI nuclear stain). Carotid sinus nerves also stain positive for TH and are seen as thin neural axons. More prominent LPAr1 staining in asthmatic OVA BN rats compared to naïve BN rats is consistent with qPCR data from Fig. 3. Top images = 20× magnification, bottom images = 63× magnification

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