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Table 11 Study 2: Galantamine reversal of hippocampal neuroimmune induction after AIE

From: Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Neuroimmune

CON-Veh

CON-Gal

AIE-Veh

AIE-Gal

HMGB1

531 ± 129 (100%)

538 ± 129 (101%)

1448 ± 136 (273%)a

601 ± 129 (113%)b

COX-2

342 ± 37 (100%)

294 ± 38 (86%)

602 ± 42 (176%)a

324 ± 38 (95%)b

  1. Data are expressed as mean ± standard error of the mean (SEM); % change relative to CON-Veh rats are represented in parentheses to the right of each datapoint
  2. aSignificantly different from CON-Veh
  3. bSignificantly different from AIE-Veh
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Journal of Neuroinflammation

ISSN: 1742-2094