Fig. 1From: NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathwayThe CCH model was established in rats. A Representative contrast and photographic images of cerebral perfusion. B CBF absolute values at the following time points: baseline, immediately after BCCAO, and 1, 2, 4, and 8 weeks after BCCAO. Baseline refers to cerebral perfusion before occlusion. C Quantification of relative CBF in ROI (% of baseline for each animal). Values are expressed as mean ± SEM (n = 3). **P < 0.01, CCH vs. sham; ##P < 0.01, NAD+ vs. shamBack to article page