Fig. 7From: NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathwayNAD+ and overexpression of Sirt1 attenuated mitochondrial injury in hypoxia-challenged BV2 microglia. A Representative image of BV2 microglia loaded with the JC-1 (red). B Flow cytometry analysis of JC-1 in BV2 microglia. Data are expressed as mean ± SEM (n = 3), *P < 0.05, **P < 0.01 vs. Hyp and Hyp + NCBack to article page