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Table 1 Comparison between favorable and unfavorable outcomes in patients receiving EVT

From: Plasma neurofilament light chain level predicts outcomes in stroke patients receiving endovascular thrombectomy

 

All patients

mRS 0–2 (n = 32)

mRS 3–6 (n = 28)

P

Age

71.2±11.8

68.4±11.3

74.4±11.6

0.04

Male sex

34 (56.7%)

23 (71.9%)

11 (39.3%)

0.01

Hypertension

39 (65.0%)

19 (59.4%)

20 (71.4%)

0.33

Diabetes mellitus

22 (36.7%)

11 (34.4%)

11 (39.3%)

0.69

Hyperlipidemia

33 (55.0%)

17 (53.1%)

16 (57.1%)

0.76

Atrial fibrillation

37 (61.7%)

16 (50.0%)

21 (75.0%)

0.046

tPA administration

16 (26.7%)

7 (21.9%)

9 (32.1%)

0.37

NIHSS

16.3±6.9

15.1±6.3

17.7±7.5

0.18

Stroke subtype

   

0.59

 Cardioembolism

43 (71.7%)

22 (68.8%)

21 (75.0%)

 

 Large-artery atherosclerosis

10 (16.7%)

5 (15.6%)

5 (17.9%)

 

 Others

7 (11.7%)

5 (15.6%)

2 (7.1%)

 

ICA/M1 occlusion

44 (73.3%)

23 (71.9%)

21 (75.0%)

0.78

Procedure time

    

 Onset-to-puncture (min)

210 (138, 360)

239 (144, 418)

203 (134, 278)

0.30

 Onset-to-recanalized (min)

234 (156, 391)

259 (159, 439)

215 (144, 336)

0.37

 mTICI 2c-3

43 (71.7%)

27 (84.4%)

16 (57.1%)

0.02

Neuroimaging

    

 ASPECTS

8 (7, 9)

9 (7, 9)

8 (7, 10)

0.38

 Initial core (ml)

20 (6, 38)

14 (3, 26)

26 (12, 47)

0.03

 Penumbra (ml)

64 (32, 89)

57 (32, 79)

65 (43, 102)

0.40

 Final infarct (ml)

13.9 (3.8, 61.4)

8.7 (1.7, 22.4)

24.5 (6.5, 139.1)

0.01

Outcome

    

 mRS score

2 (1, 4)

1 (1, 2)

5 (4, 5)

<0.001

 Mortality

4 (6.7%)

0 (0%)

4 (14.3%)

0.04

 Any ICH

20 (33.3%)

9 (28.1%)

11 (39.3%)

0.36

 Hemorrhagic infarct

14 (23.3%)

7 (21.9%)

7 (25.0%)

0.78

 Parenchymal hemorrhage

6 (10.0%)

2 (6.3%)

4 (14.3%)

0.40

  1. The Mann–Whitney U test was used for the continuous variables, whereas the chi-square test was used for the categorical variables. Bold type indicates significant results (P < 0.05)
  2. ASPECTS Alberta Stroke Program Early CT Score, ICA internal carotid artery, ICH intracerebral hemorrhage, mRS modified Rankin Scale, mTICI modified Thrombolysis in Cerebral Infarction, NIHSS National Institute of Health Stroke Scale, tPA tissue-type plasminogen activator