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Table 2 GO enrichment analysis of genes modulated in retina of DBA/2J mice, and in ONH of DBA/2J mice (GSE26299). Q-value < 0.01

From: 1α,25-dihydroxyvitamin D3 protects retinal ganglion cells in glaucomatous mice

Description

Positive regulation of cytokine production

Inflammatory response

Cytokine receptor binding

Cytokine activity

Regulation of inflammatory response

Positive regulation of response to external stimulus

Positive regulation of inflammatory response

Positive regulation of defence response

Regulation of vitamin metabolic process

Vitamin D biosynthetic process

Fat-soluble vitamin biosynthetic process

Growth factor receptor binding

Vitamin biosynthetic process

Response to tumour necrosis factor

Response to organic cyclic compound

JAK-STAT cascade

Vitamin D metabolic process

Cell-type specific apoptotic process

Fat-soluble vitamin metabolic process

Leukocyte differentiation

Regulation of leukocyte migration

Angiogenesis

Regulation of innate immune response

Vascular endothelial growth factor receptor signalling pathway

Positive regulation of vascular endothelial growth factor receptor signalling pathway

Positive regulation of T cell proliferation

Positive regulation of JAK-STAT cascade

Regulation of I-κB kinase/NF-κB signalling

Tyrosine phosphorylation of STAT protein

Interleukin-17 production

Regulation of interleukin-17 production

Leukocyte chemotaxis

I-κB kinase/NF-κB signalling

Regulation of vascular endothelial growth factor receptor signalling pathway

Growth factor activity

Regulation of angiogenesis

Cytokine biosynthetic process

Cytokine metabolic process

T cell proliferation

Regulation of vasculature development

Cellular response to interferon-gamma