Fig. 4

Coefficients of linear mixed effect models, displayed as heatmaps. The colours of the heatmaps are graded such that red represents positive coefficients and blue represents negative coefficients. All coefficients are normalized using the quotient of their standard deviation and that of the dependent variable. Significant coefficients are highlighted with an asterisk. An interaction term between female sex and infection. Independent variables are along the y-axis and the dependent variable for each model is the cytokine of the respective row on the x-axis in either A the brain extracellular fluid or B arterial blood. Differences in cytokines displayed between the two subfigures are due to insufficient data to generate all coefficients from the model