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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder

Fig. 1

Reduced frequencies of Tregs in patients with NMOSD. A The proportions and counts per microliter of circulating CD3+CD19 T cells, CD3+CD4+ cells, CD3+CD8+ cells out of CD3+CD19 T cells in HC groups (n = 21) and NMOSD (n = 25). The ratio of CD3+CD4+ cells to CD3+CD8+ cells is shown in the box-plot diagram with median and interquartile range. *p < 0.05, **p < 0.01. B Percentages of Tregs (CD3+CD4+CD25+CD127low+ T cells), effector Tregs (CD45RO+CD3+CD4+CD25+CD127low+ T cells), and naïve Tregs (CD45RA+CD3+CD4+CD25+CD127low+ T cells) among the total CD3+CD4+ cells population from HC (n = 21) and NMOSD (n = 25) groups. *p < 0.05, **p < 0.01. C The percentage of Tregs and naïve Tregs in a receiver operating characteristic model with an area under the curve value of 0.718 and 0.770 respectively

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