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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: LncRNA HOXA-AS2 regulates microglial polarization via recruitment of PRC2 and epigenetic modification of PGC-1α expression

Fig. 1

HOXA-AS2 is upregulated in the PBMCs of PD patients and in M1-polarized microglia. A The volcano figure based on lncRNAs showing differential expression patterns in PBMCs of PD patients and healthy controls. B HOXA-AS2 expression in PBMCs of PD patients and healthy controls. C RT-qPCR analysis of HOXA-AS2 in THP-1 or BV2 microglia treated with LPS or IL-4 versus the untreated control. D Representative FISH analysis of HOXA-AS2 (red) costained with anti-Iba1 antibody (green) in substantia nigra sections from LPS-treated mice. *P < 0.05, **P < 0.01, ***P < 0.001 versus control group (one-way ANOVA)

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Journal of Neuroinflammation

ISSN: 1742-2094