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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: LncRNA HOXA-AS2 regulates microglial polarization via recruitment of PRC2 and epigenetic modification of PGC-1α expression

Fig. 2

HOXA-AS2 promotes microglial M1 polarization and suppresses M2 polarization. A RT-qPCR analysis of M1 and M2 markers in microglia transfected with HOXA-AS2 small RNA (HOXA-AS2i) versus the control. B RT-qPCR analysis of M1 and M2 markers in microglia transfected with the HOXA-AS2 overexpression plasmid (HOXA-AS2oe) versus the control. C RT-qPCR analysis of M1 and M2 markers in LPS- or IL-4-stimulated BV2 cells transfected with HOXA-AS2oe or HOXA-AS2i. *P < 0.05, **P < 0.01, ***P < 0.001 versus control group. #P < 0.05, ##P < 0.01, ###P < 0.001 versus LPS- or IL-4-stimulated only groups (one-way ANOVA). The data are from three independent experiments and represented as mean ± SD

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Journal of Neuroinflammation

ISSN: 1742-2094