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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH

Fig. 2

Effect of NRBF2 on autophagy, endoplasmic reticulum stress, and oxidative stress after SAH. A Representative microphotographs of immunofluorescence double staining showing the localization of NRBF2 (red) with Lamp2 (green) in SAH 24 h group. n = 3. B–E Representative western blotting images and quantitative analyses of p62, LC3 II/I, and Lamp2 expression at 24 h after SAH. n = 6. F Representative microphotographs and quantitative analysis of CHOP-positive cells. n = 5. G Representative microphotographs and quantitative analysis of relative fluorescence intensity of DHE (red). n = 5. H–K Representative western blotting images and quantitative analyses of GRP78, CHOP, Romo-1 expression at 24 h after SAH. n = 6. Scale bar = 50 μm. Data are represented as mean ± SD. *P < 0.05 versus sham group. #P < 0.05 versus SAH group. &P < 0.05 versus SAH + Scr-siRNA group. @P < 0.05 versus SAH + NC-AAV group

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Journal of Neuroinflammation

ISSN: 1742-2094