Fig. 10

Immunostaining of GFAP-positive astrocytes at lesion sites of the injured cord following treatment with 20 mg/kg 17-AAG for 7 days and 14 days. a Area occupied by GFAP-positive scar-forming astrocytes within 2000 μm either side of the lesion center at 7 or 14 days after SCI. n = 6. b Statistical analysis of GFAP-positive percentage accounting for total area of 4000 μm border from six samples each 3 fields. Error bars represent the standard deviation, *P < 0.05, ^#P < 0.05, two-way ANOVA with Tukey’s test. F (1, 2) = 32.20, P = 0.0297. 14 days vehicle vs 7 days vehicle, P = 0.0151; 14 days 17-AAG vs 14 days vehicle, P = 0.0255