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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Inhibition of microglial β-glucocerebrosidase hampers the microglia-mediated antioxidant and protective response in neurons

Fig. 7

Modulation of gene expression by GCase inhibition in BV-2 cells. Total RNA was purified from BV-2 cells treated with 200 μM CBE for 48 h and the expression of selected mRNA were analysed by real-time PCR. Relative quantification of the transcript was obtained using the 2−ΔΔCt method versus the vehicle-treated samples. Data are presented as mean ±SD of n=3 independent samples measured in triplicate. Statistical significance was determined by two-way ANOVA followed by Sidak's multiple comparisons test. ***p<0.001

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Journal of Neuroinflammation

ISSN: 1742-2094