Fig. 2

NPSLE promotes cell glycolysis in the hippocampus, with increased expression of GLUT1, PDK1, and LDHA. A Glucose levels and lactate production in the hippocampus of the MLR/lpr mice were normalized to that of the control group mice, n = 6. B Glucose levels and lactate production in the cerebral cortex of the MLR/lpr mice were normalized to that of the control group mice, n = 6. C The mRNA expression of GLUT1, LDHA, and PDK1 in the hippocampus of control and MLR/lpr groups, n = 6. D Western blot quantification of GLUT1, LDHA, and PDK1 in the hippocampus of control and MLR/lpr groups, n = 4. E The mRNA expression of GLUT1, LDHA, and PDK1 in the cerebral cortex of the control and MLR/lpr groups, n = 6. F Western blot quantification of GLUT1, LDHA, and PDK1 in the cerebral cortex of control and MLR/lpr groups, n = 4. Data are presented as mean scores ± SEM, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001