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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia

Fig. 9

Longitudinal comparison of plasma cytokines in VCID mouse model. AC Plasma inflammatory cytokine levels from mice with 3 weeks of HF, and 8 weeks of HF, in both Control-Saline, and HF-Saline treated mice were measured via MILLIPLEX MAP Mouse High Sensitivity Multiplex Immunoassay. At 3 weeks of HF, HF-Saline mice had significantly higher IL-1α, MIP-1α, and MIP-2 concentrations than age-matched Control-Saline treated mice. A significant decrease in cytokine concentrations was observed in HF-Saline-treated mice from 3 to 8 weeks of HF. Data are represented with mean and ± SE. Difference in groups were tested by ANOVA

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