Fig. 2

BMD macrophages increase in sensory ganglia after nerve injury. GFP-BMT mice after being irradiated with a lead cap and unirradiated wild-type mice. Irradiated GFP-BMT mice after wearing a lead cap and unirradiated wild-type mice (a). GFP (green)- and Iba1 (red)-positive cells (b) and multiple staining showing co-localization (arrowhead) of GFP signals (green) with Iba1-positive cells (red) (c) in the contralateral (contra) and ipsilateral (ipsi) sides of the maxillary nerve region of the trigeminal ganglion on day 7 after nerve transection. The number of GFP-positive cells (n = 7/group) (d), GFP- and Iba1-positive cells (n = 7/group) (e), and GFP-negative and Iba1-positive cells or GFP- and Iba1-positive cells (n = 7/group) (f) on day 7 after nerve transection. See list of abbreviations. Scale bars are indicated. Data are represented as mean (S.D.), and differences were detected using Student’s t test (d) and Student’s t test with Welch’s correction (e, f)