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Table 3 CD4+ and CD8+ T lymphocyte subsets

From: T lymphocyte senescence is attenuated in Parkinson’s disease

 

% of total lymphocytes

Absolute cell count—cells × 109/L

Control

PD

p

Control

PD

p

CD4+

 Naïve

24.9 (14.4)

28.2 (14.6)

0.210

0.388 (0.282)

0.374 (0.183)

0.761

 Central memory

14.4 (7.3)

15.1 (7.5)

0.624

0.217 (0.115)

0.214 (0.125)

0.899

 Effector memory

6.0 (4.0)

5.7 (3.7)

0.656

0.095 (0.069)

0.082 (0.069)

0.332

 TEMRA

2.1 (3.5)

1.9 (2.4)

0.734

0.037 (0.072)

0.025 (0.032)

0.246

CD8+

 Naïve

5.3 (2.7)

5.9 (3.2)

0.313

0.080 (0.040)

0.081 (0.050)

0.967

 Central memory

2.2 (2.1)

1.9 (1.3)

0.277

0.033 (0.033)

0.027 (0.021)

0.205

 Effector memory

3.6 (3.7)

2.9 (3.6)

0.223

0.058 (0.068)

0.043 (0.041)

0.131

 TEMRA

12.6 (9.7)

10.2 (7.0)

0.121

0.213 (0.221)

0.140 (0.100)

0.019*

 CD28loCD57hi

5.9 (6.5)

4.9 (4.5)

0.327

0.100 (0.145)

0.066 (0.061)

0.087

  1. TEMRA, terminally differentiated effector memory cells re-expressing CD45RA. Comparisons were done using two-tailed unpaired t-tests. The values represent the mean (SD); *p < 0.05. Significant values are in italics