Fig. 4
From: Brain transcriptome analysis of a CLN2 mouse model as a function of disease progression
Comparison analysis of canonical pathways across ages using IPA. DEGs found in Tpp1−/− vs control mouse cerebellum (Cb) and fore- and mid-brain (F/M) regions at 2–4 months were used in the analysis. Thirty top z-scores (A) and – log of Benjamini–Hochberg corrected p-value (B) are represented as a heatmap. Orange and blue colored z-scores represent activation and suppression, respectively. Dots indicate activation scores below 1.64 for A and corrected p > 0.05 for B