Fig. 8

Inhibiting circCDC14A expression peripherally modulates neutrophil polarization. a Representative photomicrographs showing YM1 (green) and Ly6g (red) double immunostaining after tMCAO in circCon (top) or si-circCDC14A mice (bottom). Bar: 100 μm. b Quantification of Ly6g⁺ neutrophils in two groups, n = 2 field (320 μm × 320 μm) *3 different mice represented by different colors per group, no significance, Student’s t test. c N2 neutrophils (YM1⁺, Ly6g⁺) ratio in peri-infarct cortex of both groups. n = 2 field (320 μm × 320 μm) *3 different mice represented by different colors per group, ***P < 0.001, Student’s t test