Fig. 8

Repeat IL-6 serum measurements over a period of up to 50 (upper panel) or up to 80 (lower panel) days during hospitalization in patients with COVID-19 and neurological complications in 14 patients with available long-term data; each patient is represented by a different colour of symbols and connecting lines. The x-axis indicates days since first IL-6 serum measurement (median 51 days follow-up, range 30-80); if days since the first SARS-CoV-2 PCR-positive swab are considered instead, serum IL-6 was still elevated after at least (last known measurement) 35, 37, 42, 45, 48, 49, 55, 58, 64, 76, 77, 79, 88 and 95 days, respectively, in these patients (median 57 days, range 35-95), partly at high level. The triangles at the top of each panel indicate the time of LP. IL-6 interleukin-6, LP lumbar puncture