Fig. 7
MaR1 attenuates inflammation in the spinal cord of mice undergoing EAE. A–G Graph showing the quantification of different immune cell populations in the spinal cord (A), the number of CD4 + T cells expressing IL-4, IL-10, IFNγ or IL-17A (B), the percentage of CD4 + T cells expressing the CD49b, FoxP3, tBet, GATA3 or RORγ (C), the percentage of regulatory lymphocytes expressing IL-10 (D), the percentage of macrophages expressing polarization markers (E), the ratio of Ly6Clow/Ly6Chigh macrophages F and the percentage of microglial cells expressing polarization markers in the spinal cord after MaR1 or vehicle treatment. *p < 0.05; **p < 0.01; ***p < 0.001 vs. vehicle. Unpaired t-test (n = 4 per group). Data are shown as mean ± SEM