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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

Fig. 9

Lateral ventricle administration of BMSC-exos promoted neuron regeneration and the expression of BDNF in the hippocampus of mice injected with STZ. A Fluorescence detection of the hippocampal neonatal neuron marker DCX; B Statistics of the number of DCX positive cells and the quantification of the pixels of DCX positive area. C Western blot photos of Syt-1, Synapsin-1 and BDNF; D Quantification of Syt-1, Synapsin-1 and BDNF expression levels. Data are presented as means ± SEM, with n = 3 in each group (*P < 0.05, **P < 0.01)

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