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Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

Fig. 11

Effect of EDA on concentrations of IL-1β, IL-6, and TNF-α in the Hip and mPFC. A–C Concentrations of IL-1β (A), IL-6 (B), and TNF-α (C) in the hippocampal region. D–F Concentrations of IL-1β (D), IL-6 (E), and TNF-α (F) in the mPFC region. Data are presented as mean ± SEM (n = 6 per group). **p < 0.01, ***p < 0.001 versus the CON + Vehicle group. #p < 0.05, ##p < 0.01 versus the CSDS + Vehicle group

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