Fig. 4

Running exercise enhanced hippocampal glucose metabolism in APP/PS1 mice. a Representative [18]F-FDG-μPET 3D reconstruction images of WT_Sed, AD_Sed, WT_Run, and AD_Run mice. b Quantification results of the standard uptake value (SUV) in the hippocampus of WT_Sed, AD_Sed, WT_Run, and AD_Run mice. n = 5. c Pearson’s correlation between the DI of NOR and FDG uptake. Data are shown as the mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001