Fig. 2

Transcription and translation levels of C3 and S100A10 after ICH in mice. A Protein expression of C3 and S100A10 in hemorrhagic tissues after ICH [C3: F (3, 16) = 509.4, P < 0.0001; S100A10: F (3, 16) = 936.0, P < 0.0001]. The blots are representative of other replicates in those groups. B mRNA level of C3 [F (3, 16) = 93.73, P < 0.0001]. C mRNA level of S100A10 [F (3, 16) = 974.1, P < 0.0001). D expression of TNF-α [F (3, 16) = 133.8, P < 0.0001]. E expression of IL-1β [F (3, 16) = 63.40, P = 0.0001]. F Representative photographs of C3, S100A10 and GFAP co-staining of frozen sections of brain tissue at different time points after ICH. G Quantification of result in panel F [C3: F (3, 16) = 206.6, P < 0.0001; S100A10: F (3, 16) = 188.3, P < 0.0001]. H Longa scores of mice at different time points after ICH [F (3, 36) = 40.47, P < 0.0001]. The data were analyzed using one-way analysis of variance and all data are expressed as the mean ± standard deviation. *P < 0.05 represents a statistically significant difference between the two groups. Each experiment was repeated three times