Skip to main content
Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

Fig. 8

AMPK inhibition reverses the effects of irisin on neurological functions and inflammatory proteins expression at 24 h after ICH. A–C Modified Garcia test, forelimb placement test, and corner turn test. D Representative western blot images and quantitative analyses of p-AMPK/AMPK, IL-1β, TNF-α at 24 h post-ICH. Values are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 vs. sham group; #p < 0.05, ##p < 0.01 vs. ICH + vehicle group; @p < 0.05, @@p < 0.01 vs. irisin + DMSO group. Data were represented as mean ± SD. One-way ANOVA, Tukey test, n = 6/group

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094