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Table 2 Clinical and para-clinical features of double seronegative neuromyelitis optica spectrum disorder (n = 17)

From: CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage

CSF-restricted OCB

2/17

CSF pleocytosis (cell > 5/ul)

5/13

MS like lesion on brain MRI

0/17

AQP4–NMOSD like lesion on MRI

 

Large, confluent, unilateral, or bilateral subcortical or deep white matter lesion

5/17

Hypothalamic lesion

2/17

Periependymal lesion

5/17

Area postrema lesion

1/17

Brighter spotty lesion on spinal cord [24]

0/11

  1. CSF, cerebrospinal fluid; OCB, oligoclonal band; MS, multiple sclerosis; MRI, magnetic resonance imaging; AQP4–NMOSD, aquaporin-4 antibody positive neuromyelitis optica spectrum disorder
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Journal of Neuroinflammation

ISSN: 1742-2094