Fig. 1

Histopathological counts of microglia. Number of Iba-1 positive microglial cell bodies per experimental group (Control WT: n = 5–6; Infected WT: n = 5–6; Control α7nAChR^−/−: n = 5–6; Infected α7nAChR^−/−: n = 5–6) in different brain regions (cortex, hippocampus, thalamus and caudate nucleus) per 2 mm². Non-parametric two-way ANOVA (factors: age and time-point) was conducted for all brain regions and continuous variables were tested with post hoc Mann–Whitney U tests. Ranked transformation of data was performed. Data represent median ± IQR, **p ≤ 0.01