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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems

Fig. 5

Treatment of IMGLs with LPS/INFγ induces transcriptional changes that resemble many aspects of those observed in disease associated microglia. Violin plots depict how DAM genes change in IMGLs treated with Aβ (left) or LPS + INFγ (right). DAM down and DAM up genes are significantly down and upregulated, respectively, in IMGLs treated with LPS + INFγ (Wilcoxon test p = 0.02 and p = 1.46 × 10–6, respectively)

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Journal of Neuroinflammation

ISSN: 1742-2094