Table 1 Effects of high fat diet consumption on the cardiometabolic parameters of WT or TLR4-mut mice
From: TLR4 mutation protects neurovascular function and cognitive decline in high-fat diet-fed mice
Parameters | WT | TLR4-mut | ||
|---|---|---|---|---|
ND | HFD | ND | HFD | |
Body weight (g) | 38 ± 1 | 41 ± 0.8 | 36 ± 0.7 | 39 ± 0.6 |
Abdominal fat (g) | 1.53 ± 0.1 | 2.47 ± 0.2** | 1.7 ± 0.1 | 1.9 ± 0.1# |
Body fat (%) | 35.6 ± 1.4 | 47.2 ± 1.5** | 37.5 ± 2.9 | 43.3 ± 1.2 |
SBP (mmHg) | 94.5 ± 1.3 | 151.4 ± 2.4* | 94.1 ± 2.5 | 98.7 ± 2.9# |
Fasting glucose (mg/dl) | 101.3 ± 13.5 | 170.9 ± 10.7** | 122.7 ± 8.2 | 129.6 ± 7.5# |
Fasting insulin (ng/ml) | 0.21 ± 0.1 | 0.67 ± 0.3* | 0.29 ± 0.7 | 0.26 ± 0.7# |
HOMA-IR | 1.51 ± 0.7 | 7.82 ± 3.7* | 2.57 ± 0.7 | 2.43 ± 0.7# |
Total cholesterol (mg/dl) | 120.1 ± 18.1 | 180.2 ± 12.2* | 140.4 ± 15.6 | 139.9 ± 6.3# |
Triglycerides (mg/dl) | 59.2 ± 7.9 | 264.6 ± 29.2*** | 47.2 ± 6.4 | 58.4 ± 4.7### |