|
Characteristics
|
Discovery cohort
|
Validation cohort
|
Pa
|
Pb
|
|---|
|
PDa (N = 76)
|
HCb (N = 76)
|
p
|
PDa (N = 80)
|
HCb (N = 80)
|
p
|
|---|
|
Age (years)
|
62.2 ± 7.5
|
60.2 ± 8.2
|
0.14
|
63.7 ± 8.5
|
64.9 ± 8.8
|
0.40
|
0.25
|
0.01
|
|
Sex, N
| | | | | | | | |
|
Female
|
38
|
28
|
0.14
|
44
|
39
|
0.43
|
0.63
|
0.15
|
|
Male
|
38
|
48
| |
36
|
41
| | | |
|
Disease duration (years)
|
4.9 ± 4.3
|
/
| |
3.6 ± 3.6
|
/
| | | |
|
UPDRS I
|
8.0 ± 6.1
|
/
|
/
|
6.2 ± 4.5
|
/
|
/
|
0.05
|
/
|
|
UPDRS II
|
11.5 ± 6.8
|
/
|
/
|
12.7 ± 6.9
|
/
|
/
|
0.28
|
/
|
|
UPDRS III
|
28.4 ± 15.1
|
/
|
/
|
35.4 ± 18
|
/
|
/
|
0.01
|
/
|
- Data are expressed as mean and standard deviation (SD), as appropriate
- Pa: comparation of PD participants between discovery and validation cohort; Pb: comparation of HC participants between discovery and validation cohort
- PD Parkinson’s disease, UPDRS Unified Parkinson's Disease Rating Scale
