Table 5 Evaluation of four biomarkers for PD motor progression
Progression (n = 17) | Non-progression (n = 22) | HR (95% CI) | p value | |
|---|---|---|---|---|
Age (y) | 68.0 ± 6.7 | 68.8 ± 8.5 | / | 0.75 |
Sex, N | ||||
Male | 12 | 14 | / | 0.74 |
Female | 5 | 8 | ||
CX3CL1 | ||||
Decreased | 9 | 4 | 2.86 (1.08–7.69) | 0.036 |
Increased | 8 | 18 | ||
IL-8 | ||||
Increased | 7 | 13 | 0.44 (0.16–1.88) | 0.10 |
Decreased | 10 | 9 | ||
CXCL12 | ||||
Increased | 2 | 7 | 0.53 (0.12–2.34) | 0.40 |
Decreased | 15 | 15 | ||
MIP-5 | ||||
Increased | 12 | 19 | 1.09 (0.37–3.24) | 0.88 |
Decreased | 7 | 3 | ||