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Table 5 Evaluation of four biomarkers for PD motor progression

From: Parkinson's disease peripheral immune biomarker profile: a multicentre, cross-sectional and longitudinal study

  Progression (n = 17) Non-progression (n = 22) HR (95% CI) p value
Age (y) 68.0 ± 6.7 68.8 ± 8.5 / 0.75
Sex, N  
 Male 12 14 / 0.74
 Female 5 8
CX3CL1  
 Decreased 9 4 2.86 (1.08–7.69) 0.036
 Increased 8 18
IL-8  
 Increased 7 13 0.44 (0.16–1.88) 0.10
 Decreased 10 9
CXCL12  
 Increased 2 7 0.53 (0.12–2.34) 0.40
 Decreased 15 15
MIP-5  
 Increased 12 19 1.09 (0.37–3.24) 0.88
 Decreased 7 3
  1. Cox proportional hazards regression models were used to estimate HRs, with 95% CI adjusted for age and sex
  2. The bold emphasis in the table means p < 0.05
  3. HR hazard ratio, 95 CI 95 confidence interval