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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Activation of locus coeruleus-spinal cord noradrenergic neurons alleviates neuropathic pain in mice via reducing neuroinflammation from astrocytes and microglia in spinal dorsal horn

Fig. 8

Co-expression of TNF-α, IL-1β with GFAP in the SDH. A Colocalization of TNF-α (red) and GFAP (green) in the SDH following CCI. Not too much colocalized astrocytes (yellow) can be seen in mice with CCI. B The representative images of double immunofluorescence staining showing that IL-1β (red) is not well colocalized with GFAP (green) in SDH. C, D Shown in relative number and in percentage, colocalization of TNF-α and GFAP in groups was comparable. E, F Shown in relative number and in percentage, colocalization of IL-1β and GFAP in groups was comparable. Scale bars = 100 μm. Data are expressed as mean + SEM, n = 6, 5 slices for each mouse

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Journal of Neuroinflammation

ISSN: 1742-2094