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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration

Fig. 6

Myelin clearance in the distal sciatic nerve is unaffected in all the conditional Ccl2 knockouts 7 days after injury. A–H Representative images of myelin stained with Luxol Fast Blue (LFB) in uninjured (A, C, E, G) and injured (B, D, F, H) sciatic nerves. In all genotypes, myelin has almost completely degenerated and been cleared by 7 DPI. Scale bar is 50 µm. I Myelin clearance was quantified by LFB area and plotted as mean ± SEM. # Indicates a significant (p < 0.05) difference between Sh and Ax within a genotype. n = 10 for all genotypes except DCKO n = 9

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Journal of Neuroinflammation

ISSN: 1742-2094