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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Electrical stimulation of the splenic nerve bundle ameliorates dextran sulfate sodium-induced colitis in mice

Fig. 4

SpNS induces transcriptomic changes in the spleen. A Heatmap of the top 50 differentially expressed genes when comparing sham and SpNS mice. B GSEA plots showing depletion and enrichment of HIF-1 signaling pathway and Oxidative phosphorylation pathway associated genes among the SpNS mice. SpNS splenic nerve plexus stimulation, GSEA gene set enrichment analysis, NES normalized enrichment score, HIF hypoxia-inducible factor

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